Building a resilient application is a top priority for any business that values uptime and customer satisfaction. Multi-region architectures offer an excellent way to enhance resilience by distributing the workload across various geographical areas. However, designing such systems comes with challenges that must be carefully addressed to ensure both operational efficiency and reliability. In this article, we will explore the best practices for designing multi-region applications, with specific examples and detailed explanations. By the end, you will understand how to build a robust system that handles failures gracefully.